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A Secondary Isotope Effect Study of Equine Serum Butyrylcholinesterase-Catalyzed Hydrolysis of Acetylthiocholine

β-Secondary deuterium isotope effects have been measured for equine serum butyrylcholinesterase-catalyzed hydrolysis of acetyl-L(3)-thiocholine (L = H or (2)H). The dependencies of initial rates on isotopic substrate concentrations show close adherence to Michaelis-Menten kinetics, and yield the fol...

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Detalhes bibliográficos
Main Authors: Wiley, Kenneth L., Tormos, Jose R., Quinn, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912972/
https://ncbi.nlm.nih.gov/pubmed/20493178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.05.007
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