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A viral vaccine encoding PSA induces antigen spreading to a common set of self proteins in prostate cancer patients

PURPOSE: We previously reported a randomized phase II clinical trial combining a poxvirus-based vaccine encoding PSA with radiotherapy in patients with localized prostate cancer. Here we investigate whether vaccination against PSA induced immune responses to additional tumor-associated antigens and...

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Autors principals: Nesslinger, Nancy J., Ng, Alvin, Tsang, Kwong-Yok, Ferrara, Theresa, Schlom, Jeff, Gulley, James L., Nelson, Brad H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912964/
https://ncbi.nlm.nih.gov/pubmed/20562209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0948
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