Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation

The first line of host defense is the innate immune system that includes coagulation factors and pattern recognition molecules, one of which is mannose-binding lectin (MBL). Previous studies have demonstrated that MBL deficiency increases susceptibility to infection. Several mechanisms are associate...

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Détails bibliographiques
Auteurs principaux: Takahashi, Kazue, Chang, Wei-Chuan, Takahashi, Minoru, Pavlov, Vasile, Ishida, Yumi, La Bonte, Laura, Shi, Lei, Fujita, Teizo, Stahl, Gregory L., Van Cott, Elizabeth M.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912947/
https://ncbi.nlm.nih.gov/pubmed/20399528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2010.02.005
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