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Breath Formate Is a Marker of Airway S-Nitrosothiol Depletion in Severe Asthma

BACKGROUND: Children with severe asthma have poor symptom control and elevated markers of airway oxidative and nitrosative stress. Paradoxically, they have decreased airway levels of S-nitrosothiols (SNOs), a class of endogenous airway smooth muscle relaxants. This deficiency results from increased...

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Autors principals: Greenwald, Roby, Fitzpatrick, Anne M., Gaston, Benjamin, Marozkina, Nadzeya V., Erzurum, Serpil, Teague, W. Gerald
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912922/
https://ncbi.nlm.nih.gov/pubmed/20689836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011919
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