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Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule

BACKGROUND: Different isoforms of Cytochrome P450 (CYP) metabolized different types of substrates (or drugs molecule) and make them soluble during biotransformation. Therefore, fate of any drug molecule depends on how they are treated or metabolized by CYP isoform. There is a need to develop models...

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Hlavní autoři: Mishra, Nitish K, Agarwal, Sandhya, Raghava, Gajendra PS
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912882/
https://ncbi.nlm.nih.gov/pubmed/20637097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-10-8
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