Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis

PURPOSE: We aimed to study the intracellular expression of 5-lipoxygenase (5-LOX), the primary competitor with cyclooxygenase-2 in arachidonic acid metabolism, as inflammatory enzymes may be involved in blocking apoptosis and promoting cancer growth by changing arachidonic acid metabolism within cel...

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Detalhes bibliográficos
Main Authors: Wasilewicz, Michał P., Kołodziej, Blanka, Bojułko, Teresa, Kaczmarczyk, Mariusz, Sulżyc-Bielicka, Violetta, Bielicki, Dariusz, Ciepiela, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912725/
https://ncbi.nlm.nih.gov/pubmed/20549218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00384-010-0980-z
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