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Pharmacological or Genetic Inactivation of the Serotonin Transporter Improves Reversal Learning in Mice

Growing evidence supports a major contribution of cortical serotonin (5-hydroxytryptamine, 5-HT) to the modulation of cognitive flexibility and the cognitive inflexibility evident in neuropsychiatric disorders. The precise role of 5-HT and the influence of 5-HT gene variation in mediating this proce...

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Main Authors: Brigman, Jonathan L., Mathur, Poonam, Harvey-White, Judith, Izquierdo, Alicia, Saksida, Lisa M., Bussey, Timothy J., Fox, Stephanie, Deneris, Evan, Murphy, Dennis L., Holmes, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912649/
https://ncbi.nlm.nih.gov/pubmed/20032063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhp266
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