A serum-stable branched dimeric anti-VEGF peptide blocks tumor growth via anti-angiogenic activity

Angiogenesis is critical and indispensable for tumor progression. Since VEGF is known to play a central role in angiogenesis, the disruption of VEGF-VEGF receptor system is a promising target for anti-cancer therapy. Previously, we reported that a hexapeptide (RRKRRR, RK6) blocked the growth and met...

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Autors principals: Kim, Jung-Wook, Kim, Tae-Dong, Hong, Bok Sil, Kim, Oh Youn, Yoon, Wan-Hee, Chae, Chi-Bom, Gho, Yong Song
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Biochemistry and Molecular Biology 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912478/
https://ncbi.nlm.nih.gov/pubmed/20543548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.7.052
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