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Vitamin C distribution and retention in the mouse brain

Vitamin C (VC) is a crucial antioxidant in the brain. To assess whether different brain regions vary in their sensitivity to oxidative stress induced by VC depletion, we used the gulonolactone oxidase (gulo) knockout mouse. This mouse, like humans, cannot synthesize VC and thus its tissue VC levels...

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Detalhes bibliográficos
Main Authors: Harrison, Fiona E, Green, Roslyn J, Dawes, Sean M, May, James M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912448/
https://ncbi.nlm.nih.gov/pubmed/20570663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.05.090
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