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Genome-Wide Analysis Reveals Novel Genes Essential for Heme Homeostasis in Caenorhabditis elegans

Heme is a cofactor in proteins that function in almost all sub-cellular compartments and in many diverse biological processes. Heme is produced by a conserved biosynthetic pathway that is highly regulated to prevent the accumulation of heme—a cytotoxic, hydrophobic tetrapyrrole. Caenorhabditis elega...

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Detalhes bibliográficos
Main Authors: Severance, Scott, Rajagopal, Abbhirami, Rao, Anita U., Cerqueira, Gustavo C., Mitreva, Makedonka, El-Sayed, Najib M., Krause, Michael, Hamza, Iqbal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912396/
https://ncbi.nlm.nih.gov/pubmed/20686661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001044
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