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Requirement of Male-Specific Dosage Compensation in Drosophila Females—Implications of Early X Chromosome Gene Expression

Dosage compensation equates between the sexes the gene dose of sex chromosomes that carry substantially different gene content. In Drosophila, the single male X chromosome is hypertranscribed by approximately two-fold to effect this correction. The key genes are male lethal and appear not to be requ...

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Detalhes bibliográficos
Main Authors: Gladstein, Natalie, McKeon, Meghan N., Horabin, Jamila I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912388/
https://ncbi.nlm.nih.gov/pubmed/20686653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001041
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