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Autosomal Recessive Polycystic Kidney Disease Epithelial Cell Model Reveals Multiple Basolateral Epidermal Growth Factor Receptor Sorting Pathways

Sorting and maintenance of the EGF receptor on the basolateral surface of renal epithelial cells is perturbed in polycystic kidney disease and apical expression of receptors contributes to severity of disease. The goal of these studies was to understand the molecular basis for EGF receptor missortin...

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Autors principals: Ryan, Sean, Verghese, Susamma, Cianciola, Nicholas L., Cotton, Calvin U., Carlin, Cathleen R.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912358/
https://ncbi.nlm.nih.gov/pubmed/20519437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-12-1059
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