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A Rapid Transient Increase in Hyaluronan Synthase-2 mRNA Initiates Secretion of Hyaluronan by Corneal Keratocytes in Response to Transforming Growth Factor β

Keratocytes of the corneal stroma produce transparent extracellular matrix devoid of hyaluronan (HA); however, in corneal pathologies and wounds, HA is abundant. We previously showed primary keratocytes cultured under serum-free conditions to secrete matrix similar to that of normal stroma, but seru...

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Detalhes bibliográficos
Main Authors: Guo, Naxin, Kanter, David, Funderburgh, Martha L., Mann, Mary M., Du, Yiqin, Funderburgh, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912154/
https://ncbi.nlm.nih.gov/pubmed/17327235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609280200
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