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NAD(P)H:quinone Oxidoreductase 1-Compromised Human Bone Marrow Endothelial Cells Exhibit Decreased Adhesion Molecule Expression and CD34(+) Hematopoietic Cell Adhesion

NAD(P)H:quinone oxidoreductase 1 (NQO1) deficiency resulting from a homozygous NQO1*2 polymorphism has been associated with an increased risk of benzene-induced myeloid toxicity and a variety of de novo and therapy-induced leukemias. Endothelial cells in human bone marrow form one of the two known h...

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Bibliografiske detaljer
Main Authors: Zhou, Hongfei, Dehn, Donna, Kepa, Jadwiga K., Siegel, David, Scott, Devon E., Tan, Wei, Ross, David
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912043/
https://ncbi.nlm.nih.gov/pubmed/20378716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.167841
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