The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction

INTRODUCTION: The impact of pro-inflammatory cytokines on neuroinflammation and cognitive function after lipopolysaccharide (LPS) challenge remains elusive. Herein we provide evidence that there is a temporal correlation between high-mobility group box 1 (HMGB-1), microglial activation, and cognitiv...

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Detalhes bibliográficos
Main Authors: Terrando, Niccolò, Rei Fidalgo, António, Vizcaychipi, Marcela, Cibelli, Mario, Ma, Daqing, Monaco, Claudia, Feldmann, Marc, Maze, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911722/
https://ncbi.nlm.nih.gov/pubmed/20470406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9019
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