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Warfarin and vitamin K intake in the era of pharmacogenetics

The considerable variability in the warfarin dose–response relationship between individuals, is explained mainly by genetic variation in its major metabolic (CYP2C9) and target (VKORC1) enzymes. Despite the predominance of pharmacogenetics, environmental factors also affect the pharmacokinetics and...

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Bibliografske podrobnosti
Main Authors: Lurie, Yael, Loebstein, Ronen, Kurnik, Daniel, Almog, Shlomo, Halkin, Hillel
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911546/
https://ncbi.nlm.nih.gov/pubmed/20653669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03672.x
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