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Breast cancer stromal fibroblasts promote the generation of CD44(+)CD24(- )cells through SDF-1/CXCR4 interaction
BACKGROUND: Breast cancer stem cells (BCSCs) have been recently identified in breast carcinoma as CD44(+)CD24(- )cells, which exclusively retain tumorigenic activity and display stem cell-like properties. Using a mammosphere culture technique, MCF7 mammosphere cells are found to enrich breast cancer...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911413/ https://ncbi.nlm.nih.gov/pubmed/20569497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-80 |
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