Fragrant Dioxane Derivatives Identify β1-Subunit-containing GABA(A) Receptors

Nineteen GABA(A) receptor (GABA(A)R) subunits are known in mammals with only a restricted number of functionally identified native combinations. The physiological role of β1-subunit-containing GABA(A)Rs is unknown. Here we report the discovery of a new structural class of GABA(A)R positive modulator...

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Autori principali: Sergeeva, Olga A., Kletke, Olaf, Kragler, Andrea, Poppek, Anja, Fleischer, Wiebke, Schubring, Stephan R., Görg, Boris, Haas, Helmut L., Zhu, Xin-Ran, Lübbert, Hermann, Gisselmann, Günter, Hatt, Hanns
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911342/
https://ncbi.nlm.nih.gov/pubmed/20511229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103309
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