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Nitric-oxide Dioxygenase Function of Human Cytoglobin with Cellular Reductants and in Rat Hepatocytes

Cytoglobin (Cygb) was investigated for its capacity to function as a NO dioxygenase (NOD) in vitro and in hepatocytes. Ascorbate and cytochrome b(5) were found to support a high NOD activity. Cygb-NOD activity shows respective K(m) values for ascorbate, cytochrome b(5), NO, and O(2) of 0.25 mm, 0.3...

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Bibliografiske detaljer
Main Authors: Gardner, Anne M., Cook, Matthew R., Gardner, Paul R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911317/
https://ncbi.nlm.nih.gov/pubmed/20511233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132340
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