Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells

To evaluate the contribution of bone marrow (BM) cells to treat neurological disorders, we examined the effectiveness of BM cells expressing the homeobox B4 (HoxB4) gene to cure mice with metachromatic leukodystrophy (MLD) through transplantation. Increased number of donor cells was observed in brai...

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Autors principals: Miyake, Noriko, Miyake, Koichi, Karlsson, Stefan, Shimada, Takashi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911255/
https://ncbi.nlm.nih.gov/pubmed/20424597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.74
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