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Differential effects of lactacystin on cytokine production in activated Jurkat cells and murine splenocytes

Previous studies have demonstrated that the proteasome inhibitor, lactacystin, suppresses cytokine production and induction of other inflammatory mediators by LPS-stimulated macrophages. The purpose of the present studies was to determine the effect of lactacystin upon the function of activated huma...

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Bibliographic Details
Main Authors: Rockwell, Cheryl E., Qureshi, Nilofer
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911229/
https://ncbi.nlm.nih.gov/pubmed/20427199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2010.03.018
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