Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases

Peptidyl-prolyl isomerases catalyze the conversion between cis and trans isomers of proline. The cyclophilin family of peptidyl-prolyl isomerases is well known for being the target of the immunosuppressive drug cyclosporin, used to combat organ transplant rejection. There is great interest in both t...

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Main Authors: Davis, Tara L., Walker, John R., Campagna-Slater, Valérie, Finerty, Patrick J., Paramanathan, Ragika, Bernstein, Galina, MacKenzie, Farrell, Tempel, Wolfram, Ouyang, Hui, Lee, Wen Hwa, Eisenmesser, Elan Z., Dhe-Paganon, Sirano
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911226/
https://ncbi.nlm.nih.gov/pubmed/20676357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000439
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