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Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius: Electrical Properties of Glucagon-Like Peptide 1 Neurons

OBJECTIVE: Glucagon-like peptide (GLP)-1 inhibits food intake, acting both in the periphery and within the central nervous system. It is unclear if gut-derived GLP-1 can enter the brain, or whether GLP-1 from preproglucagon (PPG) cells in the lower brainstem is required to activate central GLP-1 rec...

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Detaylı Bibliyografya
Asıl Yazarlar: Hisadome, Kazunari, Reimann, Frank, Gribble, Fiona M., Trapp, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911066/
https://ncbi.nlm.nih.gov/pubmed/20522593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0128
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