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C-Terminal Cleavage of ΔNp63α Is Associated with TSA-Induced Apoptosis in Immortalized Corneal Epithelial Cells

PURPOSE. In the central human corneal epithelium, loss of ΔNp63 occurs in all surface epithelial cells preparing to undergo desquamation, suggesting a potential role for ΔNp63 isoforms in mediating surface cell apoptotic shedding. In this study, the authors investigated a role for ΔNp63 isoforms in...

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Detalhes bibliográficos
Main Authors: Robertson, Danielle M., Ho, Su-Inn, Cavanagh, H. Dwight
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910636/
https://ncbi.nlm.nih.gov/pubmed/20375332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4919
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