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Chip-based Reversed-phase Liquid Chromatography-Mass Spectrometry of Permethylated N-linked Glycans: a Potential Methodology for Cancer-biomarker Discovery

The study of protein glycosylation in biological fluids and tissues has substantial medical importance, as changes in glycan structures have now been associated with a number of diseases. Quantification of glycomic-profile changes is becoming increasingly important in the search for disease biomarke...

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Bibliographic Details
Main Authors: Alley, William R., Madera, Milan, Mechref, Yehia, Novotny, Milos V.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910595/
https://ncbi.nlm.nih.gov/pubmed/20491449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac100131e
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