Investigation on the Interactions of NiCR and NiCR-2H with DNA

We report here a biophysical and biochemical approach to determine the differences in interactions of NiCR and NiCR-2H with DNA. Our goal is to determine whether such interactions are responsible for the recently observed differences in their cytotoxicity toward MCF-7 cancer cells. Viscosity measure...

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Bibliographic Details
Main Authors: Chitranshi, Priyanka, Chen, Chang-Nan, Jones, Patrick R., Faridi, Jesika S., Xue, Liang
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910472/
https://ncbi.nlm.nih.gov/pubmed/20671951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/619436
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