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Disposition of Naltrexone after Intravenous Bolus Administration in Wistar Rats, Low-Alcohol-Drinking Rats and High-Alcohol-Drinking Rats

Reports have shown that interspecies differences in the metabolism and pharmacokinetics of naltrexone are a rule rather than exception. However, there is paucity of information on the disposition of naltrexone in selectively bred rat lines that reliably exhibit high and low voluntary alcohol consump...

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Detalhes bibliográficos
Main Authors: Akala, Emmanuel O., Wang, Hu, Adedoyin, Adedayo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910369/
https://ncbi.nlm.nih.gov/pubmed/18832863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000159776
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