Development of a Non-integrating Rev-dependent Lentiviral Vector Carrying Diphtheria Toxin A Chain and Human TRAF6 to Target HIV Reservoirs

Persistence of HIV despite highly active antiretroviral therapy (HAART) is a lasting challenge to virus eradication. To develop a strategy complementary to HAART, we constructed a series of Rev-dependent lentiviral vectors carrying diphtheria toxin A chain (DT-A) and its attenuated mutants, as well...

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Detalhes bibliográficos
Main Authors: Wang, Zhirui, Tang, Zhongwei, Zheng, Yanfang, Yu, Dongyang, Spear, Mark, Iyer, Subashini R., Bishop, Barney, Wu, Yuntao
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910233/
https://ncbi.nlm.nih.gov/pubmed/20410930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.53
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