BCG vaccination in the cotton rat (Sigmodon hispidus ) infected by the pulmonary route with virulent Mycobacterium tuberculosis

To evaluate the usefulness of the American cotton rat (Sigmodon hispidus) in the evaluation of vaccine-induced resistance, we infected BCG-vaccinated and non-vaccinated cotton rats with Mycobacterium tuberculosis (H37Rv) via the respiratory route. Lung histopathology of these animals showed loose, d...

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Hlavní autoři: McFarland, Christine T., Ly, Lan, Jeevan, Amminikutty, Yamamoto, Toshiko, Weeks, Bradley, Izzo, Angelo, McMurray, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910192/
https://ncbi.nlm.nih.gov/pubmed/20451457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2010.03.014
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