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Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 gene

A strong, negative cis-element located at the first intron +502/+835 (I300) of zebrafish myf5 has been reported. To elucidate the molecular mechanism underlying this repression network, we microinjected zebrafish single-cell embryos with I300 RNA, resulting in the dramatic reduction of luciferase ac...

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Hlavní autoři: Hsu, Ren-Jun, Lin, Cheng-Yung, Hoi, Hao-Seong, Zheng, Shu-Kai, Lin, Chiu-Chun, Tsai, Huai-Jen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910042/
https://ncbi.nlm.nih.gov/pubmed/20236986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq148
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