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Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear and non-linear data analysis techniques

BACKGROUND: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as cancer. Kinase inhibitors have potential for treatment of these diseases. However, current inhibitors interact with a broad v...

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Bibliografische gegevens
Hoofdauteurs: Lapins, Maris, Wikberg, Jarl ES
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910025/
https://ncbi.nlm.nih.gov/pubmed/20569422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-339
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