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Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1

BACKGROUND: Nm23 gene was isolated as a metastatic suppressor gene. The antimetastatic effect of Nm23 has been an enigma for more than 10 years. Little is known about its molecular mechanisms. In this study we overexpressed Nm23-H1 in H7721 cells and observed reduction of cell adhesion, migration an...

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Main Authors: She, Shangyang, Xu, Boying, He, Min, Lan, Xiuwan, Wang, Qiuyan
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909969/
https://ncbi.nlm.nih.gov/pubmed/20618991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-93
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