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A cohort study of recurrence patterns among more than 54,000 relatives of oral cleft cases in Denmark: support for the multifactorial threshold model of inheritance

OBJECTIVES: To determine if the anatomical severity of oral clefting affects familial recurrence in a large population based sample. To provide reliable recurrence risk estimates for oral cleft for first-, second-, and third-degree relatives. DESIGN: Population based cohort study SETTING: Denmark PA...

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Библиографические подробности
Главные авторы: Grosen, Dorthe, Chevrier, Cécile, Skytthe, Axel, Bille, Camilla, Mølsted, Kirsten, Sivertsen, Åse, Murray, Jeffrey C, Christensen, Kaare
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909851/
https://ncbi.nlm.nih.gov/pubmed/19752161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2009.069385
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