Age-related T-cell cytokine profile parallels corneal disease severity in Sjögren’s syndrome-like keratoconjunctivitis sicca in CD25KO mice*

Objectives. IL-2rα (CD25)(−/−) mice develop autoimmunity and lymphoproliferative disorders, including SS-like disease. The objective of this study was to evaluate the severity of corneal epithelial disease and T-cell cytokine profile in the ocular surface tissues of CD25KO mice. Methods. CD25KO mice...

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Autors principals: De Paiva, Cintia S., Hwang, Cindy S., Pitcher, John D., Pangelinan, Solherny B., Rahimy, Ehsan, Chen, Wei, Yoon, Kyung-Chul, Farley, William J., Niederkorn, Jerry Y., Stern, Michael E., Li, De-Quan, Pflugfelder, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Basic Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909796/
https://ncbi.nlm.nih.gov/pubmed/20007286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kep357
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