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Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization

NMDA receptor-dependent synaptic modifications, such as long-term potentiation (LTP) and long-term depression (LTD), are essential for brain development and function. LTD occurs mainly by the removal of AMPA receptors from the postsynaptic membrane, but the underlying molecular mechanisms remain unc...

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Detalles Bibliográficos
Main Authors: Li, Zheng, Jo, Jihoon, Jia, Jie-Min, Lo, Shih-Ching, Whitcomb, Daniel J., Jiao, Song, Cho, Kwangwook, Sheng, Morgan
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909748/
https://ncbi.nlm.nih.gov/pubmed/20510932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.053
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