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Identifying the Role of Specific Motifs in the Lens Fiber Cell–Specific Intermediate Filament Phakosin

PURPOSE: Phakosin and filensin are lens fiber cell–specific intermediate filament (IF) proteins. Unlike every other cytoplasmic IF protein, they assemble into a beaded filament (BF) rather than an IF. Why the lens fiber cell requires two unique IF proteins and why and how they assemble into a struct...

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Main Authors: Pittenger, Joshua T., Hess, John F., FitzGerald, Paul G.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909742/
https://ncbi.nlm.nih.gov/pubmed/17962466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0647
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