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Does Body Weight Influence the Response to Intravenous Tissue Plasminogen Activator in Stroke Patients?

BACKGROUND: The recommended dose of IV tissue plasminogen activator (t-PA) for ischemic stroke patients weighing >100 kg (ISPW >100 kg) is fixed at 90 mg. Elevated levels of plasminogen activator inhibitor-1 (PAI-1) and impaired fibrinolysis have been reported in heavy patients, suggesting tha...

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Autori principali: Lou, Min, Selim, Magdy
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909710/
https://ncbi.nlm.nih.gov/pubmed/19033683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000175766
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