Effect of pazopanib on tumor microenvironment and liposome delivery

Pathological angiogenesis creates an abnormal microenvironment in solid tumors, characterized by elevated interstitial fluid pressure (IFP) and hypoxia. Emerging theories suggest that judicious downregulation of pro-angiogenic signaling pathways may transiently “normalize” the vascular bed, making i...

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Bibliographische Detailangaben
Hauptverfasser: Tailor, Tina D., Hanna, Gabi, Yarmolenko, Pavel S., Dreher, Matthew R., Betof, Allison S., Nixon, Andrew B., Spasojevic, Ivan, Dewhirst, Mark W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909540/
https://ncbi.nlm.nih.gov/pubmed/20515941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0856
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