Membrane insertion of the FYVE domain is modulated by pH

The FYVE domain associates with phosphatidylinositol 3-phosphate [PtdIns(3)P] in membranes of early endosomes and penetrates bilayers. Here, we detail principles of membrane anchoring and show that the FYVE domain insertion into PtdIns(3)P-enriched membranes and membrane-mimetics is substantially in...

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Detaylı Bibliyografya
Asıl Yazarlar: He, Ju, Vora, Mohsin, Haney, Rachel M., Filonov, Grigory S., Musselman, Catherine A., Burd, Christopher G., Kutateladze, Andrei G., Verkhusha, Vladislav V., Stahelin, Robert V., Kutateladze, Tatiana G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909462/
https://ncbi.nlm.nih.gov/pubmed/19296456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22392
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