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Leishmania donovani-induced expression of signal regulatory protein α on Kupffer cells enhances hepatic invariant NKT-cell activation

Signal regulatory protein α (SIRPα) and its cognate ligand CD47 have been documented to have a broad range of cellular functions in development and immunity. Here, we investigated the role of SIRPα–CD47 signalling in invariant NKT (iNKT) cell responses. We found that CD47 was required for the optima...

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Bibliografische gegevens
Hoofdauteurs: Beattie, Lynette, Svensson, Mattias, Bune, Alison, Brown, Najmeeyah, Maroof, Asher, Zubairi, Soombul, Smith, Katharine R, Kaye, Paul M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: WILEY-VCH Verlag 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909397/
https://ncbi.nlm.nih.gov/pubmed/19877019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939863
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