Ironing out the wrinkles in the rare biosphere through improved OTU clustering

Deep sequencing of PCR amplicon libraries facilitates the detection of low-abundance populations in environmental DNA surveys of complex microbial communities. At the same time, deep sequencing can lead to overestimates of microbial diversity through the generation of low-frequency, error-prone read...

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Bibliographic Details
Main Authors: Huse, Susan M, Welch, David Mark, Morrison, Hilary G, Sogin, Mitchell L
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909393/
https://ncbi.nlm.nih.gov/pubmed/20236171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-2920.2010.02193.x
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