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Phenotypic robustness conferred by apparently redundant transcriptional enhancers

Genes include cis-regulatory regions that contain transcriptional enhancers. Recent reports have shown that developmental genes often possess multiple discrete enhancer modules that drive transcription in similar spatio-temporal patterns1-4: primary enhancers located near the basal promoter and seco...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Frankel, Nicolás, Davis, Gregory K., Vargas, Diego, Wang, Shu, Payre, François, Stern, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909378/
https://ncbi.nlm.nih.gov/pubmed/20512118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09158
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