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PECAM-1 is a negative regulator of laminin-induced platelet activation

BACKGROUND: Interaction of resting platelets with exposed components of the subendothelial matrix is an important early activating event that takes place at sites of vascular injury. Platelet responses to collagen are mediated by the integrin α2β1 and the glycoprotein (GP)VI/Fc receptor (FcR)γ chain...

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Main Authors: Crockett, Jimmy, Newman, Debra K., Newman, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909358/
https://ncbi.nlm.nih.gov/pubmed/20403098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03883.x
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