Functional Analysis of the Highly Antigenic Outer Capsid Protein, Hoc, a Virus Decoration Protein from T4-like Bacteriophages

Bacteriophage T4 is decorated with 155 copies of the highly antigenic outer capsid protein, Hoc. The Hoc molecule (40 kDa) is present at the center of each hexameric capsomer and provides a good platform for surface display of pathogen antigens. Biochemical and modeling studies show that Hoc consist...

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Hauptverfasser: Sathaliyawala, Taheri, Islam, Mohammad Z., Li, Qin, Fokine, Andrei, Rossmann, Michael G., Rao, Venigalla B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909354/
https://ncbi.nlm.nih.gov/pubmed/20497329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07219.x
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