The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis

Rhizopus oryzaeis the most common cause of mucormycosis, an angioinvasive fungal infection that causes more then 50% mortality rate despite first-line therapy. Clinical and animal model data clearly demonstrate that the presence of elevated available serum iron predisposes the host to mucormycosis....

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Main Authors: Ibrahim, Ashraf S., Gebremariam, Teclegiorgis, Lin, Lin, Luo, Guanpingsheng, Husseiny, Mohamed I., Skory, Christopher D., Fu, Yue, French, Samuel W., Edwards, John E., Spellberg, Brad
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909342/
https://ncbi.nlm.nih.gov/pubmed/20545847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07234.x
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