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Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells
Krüppel-like factor 6 (Klf6; copeb in zebrafish) is a zinc-finger transcription factor and tumor suppressor gene. Klf6(−/−) mice have defects in hematopoiesis and angiogenesis and do not form a liver. However, the vascular abnormalities in Klf6(−/−) mice obfuscate its role in liver development since...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909330/ https://ncbi.nlm.nih.gov/pubmed/20430021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.04.018 |
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