Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation

Invadopodia are actin-based projections enriched with proteases, which invasive cancer cells use to degrade the extracellular matrix (ECM). The Phox homology (PX)-Src homology (SH)3 domain adaptor protein Tks5 (also known as SH3PXD2A) cooperates with Src tyrosine kinase to promote invadopodia format...

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Bibliografiske detaljer
Main Authors: Stylli, Stanley S., I, Stacey T. T., Verhagen, Anne M., Xu, San San, Pass, Ian, Courtneidge, Sara A., Lock, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909319/
https://ncbi.nlm.nih.gov/pubmed/19596797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.046680
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