Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth

Children grow, but adults do not. The cessation of growth in multiple organs is the end result of a progressive decline in cell proliferation beginning in early life. The mechanisms responsible for this growth deceleration are largely unknown. Using expression microarray and real-time PCR, we identi...

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Bibliographic Details
Main Authors: Lui, Julian C., Forcinito, Patricia, Chang, Maria, Chen, Weiping, Barnes, Kevin M., Baron, Jeffrey
Format: Artigo
Language:Inglês
Published: The Federation of American Societies for Experimental Biology 2010
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909290/
https://ncbi.nlm.nih.gov/pubmed/20371622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-152835
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