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Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

BACKGROUND: Investigators designing clinical trials often use composite outcomes to overcome many statistical issues. Trialists want to maximize power to show a statistically significant treatment effect and avoid inflation of Type I error rate due to evaluation of multiple individual clinical outco...

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Bibliografiske detaljer
Main Authors: Pogue, Janice, Thabane, Lehana, Devereaux, PJ, Yusuf, Salim
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909251/
https://ncbi.nlm.nih.gov/pubmed/20529275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-10-49
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