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SOPRA: Scaffolding algorithm for paired reads via statistical optimization

BACKGROUND: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing applications, de novo assembly of moderate size genomes from such reads remains a significant challenge. These limitations could be...

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Autori principali: Dayarian, Adel, Michael, Todd P, Sengupta, Anirvan M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909219/
https://ncbi.nlm.nih.gov/pubmed/20576136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-345
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